Estius: man was made free, lord of things and God's friend, so no harm could befall him in God's friendship
To explain this, he points out that God did not make man a merely servile creature, as he made the nature of the brutes. They are therefore naturally subject to death and may be killed for men's use; indeed, some of them give way to others by death to serve as food. God made man, like the angels, free by nature and lord of other things, and besides that, through grace and righteousness, a kind of companion and friend of God himself.
From this, he says, it is clear enough that man was so made that nothing hostile would befall him as long as he remained in God's friendship. Two pairs would always go together and follow from each other: being good and being happy, and likewise being innocent and being free of misery.
And this law is so permanent, because divine justice requires it, that if it were removed the order of the universe would be disfigured.
Latin
IX. Ad cujus rei intelligentiam monet hominem non esse a Deo institutum ut creaturam mere servilem, sicut instituta est brutorum natura, quae proinde naturaliter & morti sunt obnoxia, & pro utilitate hominum occidi possunt: imo & alia aliis per mortem in usum nutrimenti cedunt: sed Deum fecisse hominem, perinde ut angelos, natura sua liberum, & aliarum rerum Dominum, atque insuper ipsius Dei per gratiam & justitiam velut socium & amicum. Indeque satis intelligi sic hominem institutum esse, ut ei nihil adversum accideret, quamdiu in Dei amicitia permaneret: sed futurum ut semper juncta essent, seque invicem consequerentur haec duo: bonum esse & beatum esse: itemque innocentem esse & expertem esse miseriae. Et hanc legem ita esse perpetuam, sic justitia divina postulante, ut ea sublata ordo universi deformaretur.